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COVID-19 and Porphyria

Covid-19 vaccination


All patients with all forms of porphyria are strongly recommended to be vaccinated against infections, including having the vaccinations against Covid 19. Not only are these vaccines deemed safe in porphyria, Covid 19 infection itself would be considered a high risk of causing an acute attack of porphyria in patients with AIP, HCP and VP. The usual potential vaccination side effects such as temporary injection site pain and swelling, fatigue and flu-like symptoms can be seen, and can be treated with rest, fluids, paracetamol or anti-inflammatory medications. If someone with porphyria does contract Covid-19, those with acute hepatic porphyria (AIP, HCP, VP) should monitor for flaring of porphyria symptoms ie abdominal pain, nausea, headaches. As with any infection, it would be important to ensure good hydration and continued food (especially carbohydrate) intake. This can minimise the risk of a porphyria attack. If there is severe nausea or vomiting restricting oral intake, or pain is severe, then attention should be sought from a health care provider eg general practitioner or emergency department. If Covid-19 infection is severe, causing shortness of breath, this would also warrant attention.

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